I personally have a Samsung TV, but this ACR and ad stuff is why ever since the moment I took it out of the box, it has never and will never, be plugged into the internet. I simply use an Google TV plugged into it for my actual streaming, and avoid all of this ACR nonsense (yes Google has their own tracking but I want Tailscale and SmartTube). I think this is the way to do it. Just use your smart TV as a dumb TV, and move on.
I've had quite good luck asking Gemini and ChatGPT to include links to research papers for every claim they make. Not only can I review at least the abstracts but I find when I do this, they'll retract some of the hallucinations they've have made in prior messages. It almost seems (and maybe they do) in their web searching tools, reread the content they include. Thus, greatly reducing errors, with minimal extra effort on my part.
I think the thing to remember with this, as with any kind of medical procedure, is the benefits versus the risks. In many cases, if you're getting this kind of MRI contrast, there's probably a good reason for it. So even if there's some risk, it might be better than say, the cancer or something else they're looking for. I feel like this is something that's often forgot in these discussions.
So given the mostly negative comments in this thread about various companies, can anyone recommend a reasonably priced, reasonably quick, place to get your DNA sequenced and subsequently analyzed? I'm curious about a more general view as well as some specific mutations.
I've been suffering from migraines for the last month, so have channeled my (non-migraine) time into a migraine tracker to try and find the root causes. All the tracking apps I tried all have nice complex forms, which is all well and good, unless...you are having a migraine.
Rough idea is easy to use voice mode to record data, then analyze unstructured data with AI later on.
I want to track all relevant life information, so what I'm eating, meds I'm taking, headache/nausea levels, etc.
Adding records is as easy as pressing record on my apple watch and speaking some kind of information. Uses Deepgram for voice transcription since it's the best transcription API I've found.
Will then send all information through to a LLM for analysis. It has a "chat with your data" page to ask questions and try and draw conclusions.
Main webapp is done, now working on packaging it into an iOS app so I can pull biometrics from Healthkit. Will then look into releasing it, either on github or possibly in the app store. It's admittedly mostly vibe coded, so not sure if it'll be something releasable, but we'll see...
As a fellow migraineur, I feel compelled to point out that the quest for triggers and root causes is probably never going to end. The way I see it, the migraine "bucket" slowly fills up, and the final trigger is simply the drop that makes it run over.
I can suggest the research papers by Markus Dahlem for some in depth modern takes on migraine.
It's definitely bucket-like for me, and I can attest meditation empties it. Whenever I stop meditating, mental busyness and subconscious anxiety slowly build up. Half hour a day is enough to keep it away. I just keep bringing my attention back to the breath, trying to feel into the physiological need to breathe (which is usually occluded or distorted by mental activity). Whenever I feel I am actively holding to some tension, I allow myself to release it. That's all in terms of instructions, and for me it works wonders. I look at it as the equivalent of flossing for the brain ;)
Sharing because it was such an obvious insight once I discovered it and I’ve suffered from migraines for years.
Blood sugar. Turned out I was having hypos. I’ve found now that just a spoonful of honey when I feel them coming on normally reduces my migraines to headaches, which I can manage myself with paracetamol
Sorry - not directly related to your post but still perhaps useful
As a former migraineur, what worked for me was completely removing food triggers, including gluten and oxalates.
Try carnivore. No carbs, all animal products. It's reversed so many of my health problems, from pre-diabetes, skin fungus flareups, and mental fog. Over a million people are now carnivore, and the evidence in support in growing quickly.
For me, as for a lot of people, lack of sleep is the big one... if I build up 4+ hours of sleep debt over a week, I'm at risk. So anything you can do to make that easier to log, like integration with a sleep tracker, would be good.
Also, a plug for Oliver Sacks's Migraine which taught me a lot about migraine with aura.
Hey, I found that daily dose of vitamin B almost completely stopped mine. There is evidence to back this up (though I don't have the reference on me), but also be careful as excessive amounts of VB can cause nerve issues.
If it’s an iPhone app the new on device transcription api in ios26 works well and is very fast. You could also use the ondevice llm to clean up the transcription. Cheaper and more privacy friendly
My current project also revolves around using voice notes to log life events. I'd love to talk and see if we could exchange some ideas. My Gmail username is the same as my HN username.
Well, depending on the people you meet, and the roles you are in, any kind of social contact can be mentally draining, even if it is not directly obvious.
Note that even the anticipation of meeting people can be a mental load.
I lived in Breckenridge (9,600ft) for a few winters post college.
Before college, when I had last been to CO, I didn't get any altitude sickness. Post college, I discovered (by blacking out on the slopes at Vail) that I now got bad altitude sickness. It now takes me almost 2 weeks to aclimate, but once I do, boy, is it amazing.
The most fun time was when I flew home to the East Coast after being there 4 months. I felt like absolute Superman. So much energy, barely needed any sleep! I only wish those effects lasted more than 5 days...
This might be a silly question: I understand the mitochondria from the mother's egg is unusable due to disease. Why do they need a 3rd person to provide one? Is there a reason they could take one from a father's cell?
> Mitochondria in human sperm contain no or very little DNA because mtDNA is degraded while sperm cells are maturing, hence they typically do not contribute any genetic material to their offspring.
I believe the simple answer (vs complicated truth) is that the donor cell, a fertilized egg, is in a state accepting a not-quite-formed nucleus. There are no male cells that can get into that state AFAIK, possibly excepting pluripotent stem cells that are somehow convinced to undergo ovogenesis.
The truth is of course much more complicated than my limited understanding.
I use the technique of taping a microsd card with copies of my passport, credit cards, 2fa backup codes, etc, encrypted; along with a $100 to the bottom of my insole inside my shoe. Put them in a little "crack sized" ziplock, add lots of gaffers tape (so if you take the insole out it's not obvious, plus makes it a bit waterproof) and if I ever get mugged, I have enough cash to get a cab (or depending on where I am, pay a bribe) and then find a computer I can use to get my info and figure out next steps.
Normally carry a yubikey with me (2, in fact, one on me, one in my big bag at my hostel / hotel). But if I get mugged between airport - hostel, then at least I have the shoe backup.
A 3rd level is that my parents have a yubikey and 2fa backup codes for me. They dont have my passwords, but in a pinch, I can call them to read me a code.
Not my idea. You can have a lawyer that has access to all your passwords, and designate a list of trusted people that can access them in an emergency.
If something happens, your friend calls the lawyer. The lawyer calls the other friends and if enough concur releases your passwords.
Depending on how technical you and your inner circle is you can even have whatever secret the lawyer holds encrypted and a key preshared with your friends so that the lawyer cant use it or the secret is irrelevant if it leaks.
This is of course more relevant in a you drop of the face of the earth, or you are wrongfully or rightly arrested kind of scenario.
Keep an eye on FRAM storage devices. Currently you can buy a USB stick with 8 KB of storage, but that storage is designed to last 200 years (and should at least survive a few decades). You can even recover the data off it with a soldering iron and a steady hand if needed. Would be a neat solution for keeping a backup code in a safe long term (maybe once the price drops to be competitive with a laminated sheet of paper)
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