My friend Dave Taylor (programmer on Doom / Doom 2 / Quake / Abuse) was famous for marathon gaming sessions when he was at id. He told me it almost killed him after a session because he was driving and saw what he thought was a Quake rocket ammo box and he instinctively swerved the car at speed to "pick it up", but it was in fact a concrete pylon securing a guardrail by a drop-off. He narrowly swerved back into the road.
On a lighter note, I played far too much GTA: Vice City on PS2 in college, to the point that when driving in real life I forgot to check my side and back mirrors at stop signs, and instead realized I was squeezing my middle fingers on the steering wheel instead of turning my head to look.
Even closer to the mark—I used to play Carmageddon with some of the engineers at Apple when work was wrapping up for the day. Yeah, you had to come down from that very quickly when you got into your actual car then to begin the commute home.
On a lighter note, I played far too much GTA: Vice City on PS2 in college, to the point that when driving in real life I forgot to check my side and back mirrors at stop signs, and instead realized I was squeezing my middle fingers on the steering wheel instead of turning my head to look.