If you make your centrifuge big enough, it's fine.

But yeah, sticking rats in a centrifuge is probably a better first step than starting with humans.

> If you make your centrifuge big enough, it's fine

We don't know this! We don't know how (or even if) an embryo develops under the Coriolis force, or with a gravity gradient.

If you make it big enough, there's no discernible gradient and not much of a Coriolis force.