I work with less technical users and the problem with UV is that the installation instructions are slightly more complicated.
For users that just want conda to download python + a bunch of packages and won't ever bother to create environments, anaconda will always be superior.
Now, if UV bundles with a "default python version" with an installer, that may change things.
the other use case is if your env requires compiled binaries, you can't do that with uv. i.e., the Intel MKL package is available on conda but not on pypi. We've also run into this with some cuda related packages.
I work with less technical users and the problem with UV is that the installation instructions are slightly more complicated.
For users that just want conda to download python + a bunch of packages and won't ever bother to create environments, anaconda will always be superior.
Now, if UV bundles with a "default python version" with an installer, that may change things.