Doesn't Safari have basically the same limitations as Chrome with Manifest v3?

Safari isn't the solution in this case as they were actually the first ones to heavily restrict adblocking. Manifest v3 is inspired by what they did.

Safari does have heavy restrictions on extensions but I still rarely see ads with 1Blocker (Safari extension) and NextDNS. So rarely it feels like never.

It’s also opened up somewhat in recent years. While I personally stick with Safari’s Content Blocking feature for performance reasons, 1Blocker and others do have a JavaScript-based option these days.

I've had similarly good experiences with AdGuard and Wipr and prefer the latter for the UX.