Steve Jobs was historically against gaming on apple devices and, I believe, went so far as to try to remove them from the Apple Store. Apple is only recently starting to introduce gaming seriously back into the platform.
Would be incredibly fascinating to consider what if Bungie was never bought by Microsoft and Halo ended up a Mac title first. It would've severely capped the influence of the game (and maybe its quality), even after it would have been ported to PC. Would Halo have even been imported to Xbox? On the flip side, if it somehow managed to capture considerable success- would it have forced Jobs and Apple to recognize the importance of the gaming market? Either way, the entire history of video games would be altered.