"Dvaita Vedanta espouses 5 fold eternal differences between Brahman (God), Aatma (Soul/Self) and Jada (Non-living matter). Brahman is the only Independent entity - Omnipotent, Omniscient, Omnipresent, All Pervading, Eternal. Aatma is also Eternal but is always dependent on Brahman. Creation/Jada is real but temporary and will get destroyed and remade by Brahman forever[1]. All 3 are different from each other making the Prapancha (5 eternal differences). Moksha/Enlightenment/Liberation is attainment of maximum potential of Aatma resulting in permanent bliss with zero suffering (complete self-expression, self-manifestation and self-realization). All Aatmas have gradation/positions based on their Karma and go through Karmic cycle of birth and death of the bodies they inhabit. Few great Aatmas are eligible for Moksha ending their Karmic cycle of birth and death in material Creation."

I tried to fit the entire philosophy in as simple/brief words as possible. If you have more questions I will happily provide in depth answers.

[1] It is called Mahapralaya or the Great Dissolution and happens every 311.04 trillion years (or 100 Brahma Years) where everything goes back into singularity and gets recreated again through the Hiranyagarbha/Golden Womb/Big Bang.