Author and Edgemesh employee here:
I think it sits pretty squarely in the 'complimentary' category.
E.g. we've customers who run Fastly, Akamai , Cloudflare etc but add us as well to get increased resiliency, Real User Metrics and edge acceleration. One customer saw a 35% drop in page load time when they added Edgemesh to an already fast Fastly supported site. Enterprise customers use Supernodes to add capacity in via their own datacenters.