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For the sake of mutual understanding, let's say Israel are the good guys, Hamas are terrorists, and the IDF is a righteous force whose only goal in Gaza is to capture terrorists.

What happens to everyone else in Gaza? Is "starve them all" an acceptable response to a hostage situation?


Yes, the Israeli government seems convinced that hostages don't need to eat


I agree the results after one year of a keto diet don't prove much, but getting that test seems like a good idea. I hope they'll keep testing and reporting the results for years, so we can learn more about the long term effects of a keto diet. And if it does cause problems, they'll want to know ASAP.


CAC tests come with a non-trivial radiation exposure if someone is getting them every few years.

The other problem is that they’re picking and choosing which tests to believe and which to ignore.

They disregard their cholesterol tests because they don’t like the results, but embrace one or two CAC tests because they do like the results (when they’re young).

However the CAC results are a lagging indicator of cumulative damage that has been done. Cholesterol tests are correlated with the rate of damage occurring.

So embracing CAC and using it to justify ignoring LDL and others is the problem.


I think the unknown factor here is whether other benefits of keto over a standard American diet--possibly including reduced inflammation, BP, blood glucose, and body weight--balance out the effect of cholesterol. CAC measures actual damage already done, while cholesterol is just one of many factors.

The downside, of course, is that once the damage is done, it's done, so it's a risk. (And as you said, they won't see the damage in their 20s.)


In short: approximately 4% of the population of the island nation of Tuvalu will migrate to Australia each year.

I wonder what life will be like there when half the population have left. Some people will be left living in a mostly abandoned island nation for years.


Yes, that's one of the angles.


row row row your boat gently down the stream merrily merrily merrily life was but a dream

?


Who does chargebacks on Steam? They'd lose their whole account.


What makes it utopian?


Only the "best people" will live and work there, I guess.


To be clear, this is something that would be wrapped around a fusion power plant (capturing neutrons produced by fusion), not a viable fusion plant itself nor a way to generate gold from just any power plant, right?


mRNA vaccines like the Pfizer and Moderna COVID vaccines don't enter the nucleus nor have a permanent effect. The mRNA breaks down after a few days.


Do we have any studies that show this fast clearance? From what I understand at least one of them used a pseudo-uradine that there isn't an efficient direct metabolic pathway to process, which was kind of the whole point. The idea being it would circulate longer and be "more effective"


The uridine modification was intended to reduce immunogenicity of mRNA - some of our immune cells have pattern-seeking receptors in the TLR family that recognize ssRNA and dsRNA. The presence of modified uridines throws this pattern recognition off. (https://doi.org/10.1016/j.jconrel.2015.08.051)

The modifications to increase mRNA half-life concerned mostly the caps and poly(A) tail. But even with those the persistence was in the range of days (sort of depending on how sensitive a method you picked).


That's right, they use N1-Methylpseudouridine instead of uridine (the nucleoside contained in uracil, which is the U in mRNA sequences) to last a bit longer (but not forever) and to avoid triggering immune reactions to the mRNA itself (the immune system can detect foreign mRNA).

Certainly the vaccine's mRNA sequence breaks down into separate nucleotides. If it did not, continued production of the antigens would cause a chronic immune reaction and/or immune exhaustion that would make the vaccine ineffective.

I don't know what happens to the N1-Methylpseudouridine though. That's an interesting question.


> Certainly the vaccine's mRNA sequence breaks down into separate nucleotides. If it did not, continued production of the antigens would cause a chronic immune reaction and/or immune exhaustion that would make the vaccine ineffective.

I suspect you just described "long COVID" or "vaccine injury" for some fraction of folks.


Also, people are usually like LOL it's just mRNA it goes away

But evidence does show it CAN go back to DNA with mechanisms familiar to anyone edgycated in molecular genetics - https://pubmed.ncbi.nlm.nih.gov/35723296/

Now, that particular study is in whatever cell line, highly dubious how it pertains to a human body, a few steps removed. But if you say "will you see this if you vaccinate 500 million times in 500 million people each with 500 trillion cells" - yea probably you would


Numerous studies have found vax-derived spike persisting for months and even years after vaccination, giving rise to concerns expression of spike can continue long after the claimed 24-48 hours.

A recent study found spike protein persisting for 17 months in the cerebral arteries of stroke victims. [1]

[1] https://www.sciencedirect.com/science/article/pii/S096758682...


That is interesting, but the authors point out:

> In our study, in situ hybridization detected both mRNA derived from the vaccine and mRNA from the SARS-CoV-2 virus. ... our in situ hybridization method has high sensitivity and could detect trace amounts of mRNA, possibly reflecting unrecognized asymptomatic infections. These findings emphasize the need for caution in interpreting the presence of spike protein as exclusively vaccine-related.

We should also note that the study doesn't show that the original vaccine mRNA somehow survived for months, only that mRNA matching the vaccine sequence was detected by complementary probes.

I wonder if, in these cases, the vaccine was administered to someone with an active (but asymptomatic) COVID infection, and the vaccine mRNA was copied by the same RNA-dependent RNA polymerase that copies the viral RNA.

That might explain why both vaccine and viral RNA were found.


How much of that $100 million goes to Colbert himself?


Alaska's Permanent Fund dividend paid $1,702 last year (for the whole year, not monthly). How is that small amount changing people's lives?


Every person’s story is different. People are resourceful.

If $150 a month can make people’s lives better, in a state that doen’t issue its own currency, imagine what phasing in a UBI for everyone in USA can do, gradually and increasing. And that’s the point.

USA will have to print money anyway to service their sovereign debt. So may as well give it out as a UBI over 40 years first, then tax it and pay the treasury holders. Think about it!


It certainly qualifies for a rather interesting definition of "basic"


A few thousand? I would think 16 & 17 year olds in the UK would be a couple million people.


https://www.bath.ac.uk/publications/the-age-divide-in-uk-pol...

This being the first thing I found says the closest age bracket 18-34 turnout was 53.6%

https://upload.wikimedia.org/wikipedia/commons/d/d6/UK_Popul...

16-17 for each gender looks to be a little under 400K for each

So (4)(400,000)(0.536) = 857,600

So thousands.

Either way it's not like they're all going to vote one way and it's not like they can seize the government with their own special interest party that only caters to 16-17 year old even if they all managed to vote one way. So really as far as results it will mostly be a wash, but has the benefit of potentially creating some more engaged and politically active citizens which is a win for democracy.


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