Oxford Nanopore is the disruptive company putting pressure on Illumina. They're racing to the $100 genome and Nanopore is the newer, cheaper tech that Illumina is trying to mimic.
Illumina is a bloated monopoly that hasn't lowered its prices in years. They are anti-innovation.
Oxford Nanopore is currently far more expensive and lower quality than Illumina sequencing. A single minion run costs $500. It doesn’t even provide a single x1 complete human genome.
You can currently get a complete x30 human genome using Illumina or BGI sequencing for similar cost.
It’s not clear that Oxford Nanopore can reduce costs. It’s not even clear to me that the Minion runs are currently sold at a profit. The chips are quite big, and not easily reused. Fabrication costs are likely significant.
Illumina is a bloated monopoly that hasn't lowered its prices in years. They are anti-innovation.